Handyscope HS4 DIFF USB oscilloscope

A differential USB oscilloscope

Base price:  828.00

A differential 4 channel, 50 MHz USB oscilloscope from TiePie engineering.

Key specifications

  • Differential inputs
  • 12, 14, 16 bit resolution, 0.3 % DC accuracy
  • Up to 50 MS/s sampling, 50 MHz bandwidth
  • 128 KSamples memory per channel

View full specifications

Base model:
  • Handyscope HS4 DIFF-50
  • Handyscope HS4 DIFF-25
  • Handyscope HS4 DIFF-10
  • Handyscope HS4 DIFF-5

Order code:

The Handyscope HS4 DIFF is a 4 channel differential USB oscilloscope with a maximum sampling speed of 50MS/s and 128 KSamples memory per channel. The differential input channels enable safely measuring, without risk of creating a short circuit through the oscilloscope. The Handyscope HS4 DIFF is delivered with a complete measurement software package that offers all you need for your measurement applications.

Differential inputs

The Handyscope HS4 DIFF features four isolated differential input channels. This makes it the ideal instrument to perform measurements in high voltage circuits, amplifiers, switch mode power supplies, power inverters etc. No more risk of creating short circuits through your oscilloscope!

Read more about differential measuring

Fast continuous streaming

Besides measuring in block mode, the Handyscope HS4 DIFF is also capable of performing continuous streaming measurements. This will create a continuous uninterrupted data stream to the computer. The data can then be displayed on the screen and/or saved to disk.

Read more about streaming measurements

Combining multiple Handyscope HS4 DIFFs

When one Handyscope HS4 DIFF does not offer enough input channels, the Handyscope HS4 DIFF can be coupled to one or more other instruments. This allows to make a combined instrument which will enable simultaneous measuring on all channels of all combined instruments.

Read more about combining instruments

Versatile Multi Channel oscilloscope software

The Handyscope HS4 DIFF is delivered with the versatile Multi Channel oscilloscope software, which transforms the Handyscope HS4 DIFF into an oscilloscope, spectrum analyzer, data logger, multimeter and protocol analyzer.

Some of the powerful features of the Multi Channel oscilloscope software are indicated below, for a full description of the Multi Channel oscilloscope software, refer to the Multi Channel oscilloscope software pages.

Flexible signal displays

The Multi Channel oscilloscope software scope, spectrum analyzer and datalogger offer an ultimately flexible way to display all aspects of the measured signals. They can have one or more graphs, each displaying one or more signals, where each graph can display different parts of a signal. Graphs can display the signal(s) of your Handyscope in Yt mode, in XY mode or as frequency spectrum, with or without interpolation. Colors of all items in a graph can be set to any required value. Graph dimensions can be adjusted to any required size, graphs can be located in one single window or in separate windows, which can be located anywhere on the desktop.

Read more on Graphs...

Touchscreen friendly toolbars

An oscilloscope toolbar and channel toolbars are available for each detected Handyscope. The convenient toolbars provide clear buttons for all settings of the oscilloscope and its channels. They show the current settings of the oscilloscope and allow to change all settings. The large buttons are very suitable for touchscreen operation.

The toolbars are fully configurable through the program settings. You can set the button size, add or remove buttons and change the order of the buttons.

Read more on oscilloscope toolbars... Read more on channel toolbars...

Many automatic measurements

The Multi Channel oscilloscope software features many automatic measurements, that can be performed on the measured signals of your Handyscope or on a selection of the measured signals. Using the automatic measurements in the oscilloscope, any detail of your signal is revealed. Two sets of cursors, both horizontal and vertical, can be used to indicate a part of the signal that needs to be examined thoroughly. The automatic measurements include e.g.: Mininum, Maximum, Top-Bottom, RMS, Mean, Variance, Standard deviation, Frequency.

The measurement results are shown in a special value window that can be positioned anywhere on your computer screen. A convenient toolbar allows you to enable or disable a measurement with a single click. The measurement results can be copied to the clipboard e.g. to use them in reports. When printing the graphs, the cursors and measurements results are also included.

Read more on cursors and measurements...


The multimeter in the Multi Channel oscilloscope software turns your Handyscope into a multimeter can be used to measure or monitor specific properties of a signal, like True RMS value, frequency, maximum value etc. The Multi Channel oscilloscope software multimeter can have any number of fully configurable displays, either displaying the measured value as a number or using a gauge display. When using a gauge display, it can be very helpful when adjusting a circuit for a specific property, e.g. adjusting an offset to zero.

Read more on the Multimeter...

More features

To discover more features of the comprehensive Multi Channel oscilloscope software for your Handyscope HS4 DIFF, visit the Multi Channel oscilloscope software pages for a full description.

The Handyscope HS4 DIFF is available in 4 different models that distinguish in maximum sampling rate and maximum streaming rate:

Order codeMax. sampling speedMax. streaming speed
HS4-DIFF-5050 MS/s500 kS/s
HS4-DIFF-2525 MS/s250 kS/s
HS4-DIFF-1010 MS/s100 kS/s
HS4-DIFF-55 MS/s50 kS/s

Available options for the Handyscope HS4 DIFF are:

  • W5: With the extended warranty option, warranty is five years on parts and labor. Without this option, the models have two years warranty on parts and labor.

View complete list of all models

The Handyscope HS4 DIFF is delivered with:

Cary case Carry case BT341
Instrument Handyscope HS4 DIFF
Measure leads 4 x Measure lead TP-C812B, Differential BNC -> 4 mm banana plug
Differential attenuator 4 x Differential attenuator TP-DA10
Accessories external power cable for USB port
Software for Windows 7/8/10 on CD
Drivers for Windows 7/8/10 on CD
Manuals instrument manual and software user's manuals
color printed and digital on CD
Complete set

Several downloads for the Handyscope HS4 DIFF are listed below, including Multi Channel oscilloscope software, drivers and manuals.

Driver & Software

USB driver8.1.6Windows 7/8/10, 32 and 64 bit3.81 MB download
Multi Channel software1.40.3Windows 7/8/10, 32 and 64 bit, including PDF manual66.44 MB download

Manuals & Documents

Multi Channel software manual 1.07English4.86 MB download
Handyscope HS4 DIFF Instrument manual2.22English717.03 kB download
Handyscope HS4 DIFF DatasheetEnglish4.16 MB download

Software Development Kit (SDK)

Interfacing the Handyscope HS4 DIFF with third party software and developing own software requires the LibTiePie Software Development Kit. Detailed information on the LibTiePie SDK, downloads for Windows and Linux platforms and bindings and programming examples for various programming environments can be found in the LibTiePie pages.